Antibacterial activity of ronidazole.
نویسنده
چکیده
Ronidazole, a nitroimidazole that has in vivo antiparasitic and antimycoplasmal activity, also has some in vivo antibacterial activity.
منابع مشابه
Xenobiotic acyl-coenzymes A: critical intermediates in the biochemical pharmacology and toxicology of carboxylic acids.
ronidazole. The reduction of the nitro group to the amine cesults in the total loss of mutagenic activity. Furthermore, once the amine is formed, it is not re-activated like those of other aromatic amines. In conclusion, the major ronidazole-protein adduct contains a reduced nitro function, has lost the carbamoyl group, and is alkylated by cysteine at the 2-methylene or 4-position. These struct...
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1. Is it possible that, by using Ronidazole (E-759) in the feedingstuffs for turkeys, according to the conditions set up by Council Directive 70/524/EEC (1) (See background), residues with the intact nitroimidazole structures may still be present, beyond the six-day pre slaughter withdrawal period? 2. In view of (1) above, may the consumer be exposed to these residues ? and would these residues...
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quinolones are broad-spectrum antibacterial agents.they have many clinical uses which are increasing.quinolones exert antibacterial activity primarily by inhibiting bacterial DNA gyrase.the inhibition of DNA gyrase by the quinolones are greatly influenced by the nature of the C-7 substituent on the quinolones molecule.substitution of bulky functional groupd is also possible in C-7 position.furt...
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ورودعنوان ژورنال:
- Applied microbiology
دوره 22 3 شماره
صفحات -
تاریخ انتشار 1971